4,5-二溴-1H-吡咯-2-甲醛合成路线 （共 3 条）
反应条件
bromine; acetic acid in chloroform T=50°C; 16 h;
参考文献
Denton, Ross M.; An, Jie; Lindovska, Petra; Lewis, William
Tetrahedron, 2012 , vol. 68, # 13 p. 2899 - 2905
反应条件
1: 75 percent / 4 A molecular sieves / 38 h / Heating
2: 1.) t-BuLi, 3.) t-BuLi, 5.) 10percent aq. NaOH
View Scheme
参考文献
Bray, Brian L.; Hess, Petr; Muchowski, Joseph M.; Scheller, Markus E.
Helvetica Chimica Acta, 1988 , vol. 71, p. 2053 - 2057
反应条件
1: 75 percent / Heating
2: t-BuLi / tetrahydrofuran / 0.25 h / -105 °C
3: 71 percent / NaOH, H2O / methanol
View Scheme
参考文献
Bray, Brian L.; Hess, Petr; Muchowski, Joseph M.; Scheller, Markus E.
Helvetica Chimica Acta, 1988 , vol. 71, p. 2053 - 2057
