7-氟-1H-吲唑-3-羧酸甲酯合成路线 (共 2 条)
反应条件
sulfuric acid Reflux;
参考文献
Pfizer Inc.
Patent: US2011/28447 A1, 2011 ;
Location in patent: Page/Page column 40 ;
反应条件
1.1: sodium hydroxide; sodium nitrite / water / Cooling with ice 1.2: 0.17 h / 0 °C 1.3: 1 h / 0 °C 2.1: sulfuric acid / Reflux View Scheme