4,5-二氯-2-甲基哒嗪-3-酮合成路线 （共 29 条）
参考文献
Kaji, Kenji; Nagashima, Hiromu; Ohta, Yusho; Nagao, Sigeto; Hirose, Yoshihiko; Oda, Hirohisa
Heterocycles, 1984 , vol. 22, # 3 p. 479 - 484
反应条件
in water 5 h; Heating;
参考文献
Takaya,M. et al.
Journal of Medicinal Chemistry, 1979 , vol. 22, p. 53 - 58
反应条件
in water regioselective reaction;
参考文献
Haider, Norbert; Hochholdinger, Iris; Matyus, Peter; Wobus, Andrea
Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 7 p. 964 - 970
反应条件
in toluene 24 h; Ambient temperature;
参考文献
Yamasaki, Tetsuo; Kawaminami, Eiji; Uchimura, Fumi; Okamoto, Yoshinari; Okawara, Tadashi; Furukawa, Mitsuru
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 4 p. 825 - 829
反应条件
sodium nitrite in N,N-dimethyl-formamide T=90°C; 24 h;
参考文献
ASTEX TECHNOLOGY LIMITED
Patent: WO2006/3440 A1, 2006 ;
Location in patent: Page/Page column 151 ;
WO 2006/003440 A1
反应条件
NH4OH in ammonium hydroxide T=130 - 140°C; P=3.8 - 4.5 Torr; 7 h;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 50, # 2 p. 492 - 502
反应条件
1: 80 percent / NaN3 / methanol / 24 h / Heating 2: 36 percent / H2 / Pd/C / ethanol / 22 h / Ambient temperature View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 35, # 4 p. 819 - 826
反应条件
1: 80 percent / NaN3 / methanol / 24 h / Heating 2: 38 percent / H2 / Pd/C / ethanol / 22 h / Ambient temperature View Scheme
参考文献
Kweon, Deok-Heon; Kang, Young-Jin; Chung, Hyun-A.; Yoon, Yong-Jin
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 4 p. 819 - 826
反应条件
in methanol
T=20°C; 4.33333 h;
参考文献
F. HOFFMANN-LA ROCHE AG; JAESCHKE, Georg; LINDEMANN, Lothar; VIEIRA, Eric; WICHMANN, Juergen
Patent: WO2011/6910 A1, 2011 ;
Location in patent: Page/Page column 23 ;
WO 2011/006910 A1
参考文献
Jaeschke, Georg; Lindemann, Lothar; Vieira, Eric; Wichmann, Juergen
Patent: US2011/15202 A1, 2011 ;
Location in patent: Page/Page column 11 ;
