pyrrolidine; Pd(OAc)2*PPh3 4 h; Heating;

bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine T=20°C; Sonogashira coupling; Inert atmosphere;

1: 87 percent / (PPh3)2PdCl2 / 2 h / 80 °C / var. 2-bromoallyl acetates, other secondary and tertiary cyclic amines 2: pyrrolidine, triphenylphospine / palladium acetate View Scheme

1: 60 percent / (PPh3)4Pd / 5 h / 80 °C / var. 2-bromoallyl carbonates; other secondary and tertiary cyclic amines, var. Pd catalysts 2: pyrrolidine, triphenylphospine / palladium acetate View Scheme

pyrrolidine; triphenylphosphine; palladium diacetate