1,3,5-三氟-2,4-二甲基苯合成路线 (共 2 条)
反应条件
potassium hydroxide
1.) NH3(l), -40 degC, 1 h, 2.) 20 min; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Shtark, A. A.; Chuikova, T. V.; Shteingarts, V. D.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, # 5 p. 960 - 967
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 5 p. 1055 - 1063
反应条件
sodium amide in ammonia
T=-70°C; 1 h;
参考文献
Shtark, A. A.; Chuikova, T. V.; Selivanova, G. A.; Shteingarts, V. D.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, p. 2271 - 2276
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 12 p. 2574 - 2580