N-(三异丙基甲硅烷基)-3,4-二溴吡咯合成路线 （共 8 条）
反应条件
N-bromosuccinmide in tetrahydrofuran
T=-78°C; 0.5 h;
参考文献
Higashino, Tomohiro; Osuka, Atsuhiro
Chemistry - An Asian Journal, 2013 , vol. 8, # 9 p. 1994 - 2002
反应条件
N-bromosuccinmide in tetrahydrofuran
T=-78°C; 1 h; Yields of byproduct given;
参考文献
Bray, Brian L.; Mathies, Peter H.; Naef, Reto; Solas, Dennis R.; Tidwell, Thomas T.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 26 p. 6317 - 6328
反应条件
N-bromosuccinmide in tetrahydrofuran
T=23°C; 1 h; Yields of byproduct given;
参考文献
Bray, Brian L.; Mathies, Peter H.; Naef, Reto; Solas, Dennis R.; Tidwell, Thomas T.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 26 p. 6317 - 6328
反应条件
n-butyllithium; water
参考文献
Muchowski, Joseph M.; Naef, Reto
Helvetica Chimica Acta, 1984 , vol. 67, p. 1168 - 1172
反应条件
N-bromosuccinmide in tetrahydrofuran
T=23°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bray, Brian L.; Mathies, Peter H.; Naef, Reto; Solas, Dennis R.; Tidwell, Thomas T.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 26 p. 6317 - 6328
反应条件
1: 1.) NaH / 1.) DMF, 0 deg C, 1.25 h, 2.) 0 deg C, 0.75 h
2: N-bromosuccinimide (NBS) / tetrahydrofuran / 23 °C
View Scheme
参考文献
Bray, Brian L.; Mathies, Peter H.; Naef, Reto; Solas, Dennis R.; Tidwell, Thomas T.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 26 p. 6317 - 6328
反应条件
N-bromosuccinmide in tetrahydrofuran
T=-78°C; Yield given. Yields of byproduct given;
参考文献
Muchowski, Joseph M.; Naef, Reto
Helvetica Chimica Acta, 1984 , vol. 67, p. 1168 - 1172
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether
T=85°C; Suzuki-Miyaura reaction; 24 h;
参考文献
Fukuda, Tsutomu; Sudo, Ei-ichi; Shimokawa, Kozue; Iwao, Masatomo
Tetrahedron, 2008 , vol. 64, # 2 p. 328 - 338
