(R)-(-)-3-溴-2-甲基-1-丙醇合成路线 (共 5 条)
反应条件
Bradyrhizobium japonicum USDA110 haloalkane dehalogenase; water in dimethyl sulfoxide T=30°C; pH=8.2; 0.5 h; Tris-SO4 bufferEnzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron, , vol. 68, # 37 p. 7645 - 7650
反应条件
potassium carbonate in methanol; water 1 h; Ambient temperature;
参考文献
Kozikowski; Chen; Wang; Xu
Tetrahedron, 1984 , vol. 40, # 12 p. 2345 - 2358
反应条件
1: With ozone in hexane; dichloromethane T=-80°C; 0.333333 h; Inert atmosphereSchlenk technique; 2: With sodium tetrahydroborate in hexane; dichloromethane; water T=-80 - 20°C; Inert atmosphereSchlenk technique; Overall yield = 30 percent; Overall yield = 22.5 mg;
参考文献
Journal of Organic Chemistry, , vol. 78, # 17 p. 8274 - 8280
参考文献
Walsh, Louise M; Goodman, Jonathan M
Chemical communications (Cambridge, England), 2003 , # 20 p. 2616 - 2617
反应条件
in benzene
72 h; Heating;
参考文献
Kozikowski; Chen; Wang; Xu
Tetrahedron, 1984 , vol. 40, # 12 p. 2345 - 2358