5-(4-甲氧基苯基)-3-甲基-1-氧-3-氮杂并[5.5]十一烷合成路线 （共 3 条）
反应条件
1: With lithium aluminium tetrahydride in diethyl ether T=20°C; 18 h; 2: With potassium hydroxide; water in diethyl ether 0.25 h;
参考文献
Solvay Pharmaceuticals, B.V.
Patent: US2009/5455 A1, 2009 ;
Location in patent: Page/Page column 7 ;
反应条件
1: With formic acid in water
2 h; Heating / reflux;
2: With sodium hydroxide in water
T=0°C; pH=~ 10;
参考文献
Solvay Pharmaceuticals, B.V.
Patent: US2009/5455 A1, 2009 ;
Location in patent: Page/Page column 6-7 ;
反应条件
formic acid in water
T=90 - 95°C; 1 h;
参考文献
Saravanan, Mohanarangam; Kumar, Karra Suresh; Reddy, Padi Pratap; Satyanarayana, Bollikonda
Synthetic Communications, 2010 , vol. 40, # 13 p. 1880 - 1886
