2-(3,5-双(三氟甲基)苯基)乙醇合成路线 （共 4 条）
反应条件
dichloro bis(acetonitrile) palladium(II); [Ph4(η5-C4CO)2H(CO)4Ru2](μ-H); water; p-benozquinone in methanol; isopropyl alcohol
T=85°C; 36 h; Inert atmosphereGlovebox; regioselective reaction;
参考文献
Yang, Yongsheng; Guo, Jiayi; Ng, Huimin; Chen, Zhiyong; Teo, Peili
Chemical Communications, 2014 , vol. 50, # 20 p. 2608 - 2611
反应条件
borane-THF in tetrahydrofuran
T=0°C; 4 h;
参考文献
Avery, Mitchell A.; Alvim-Gaston, Maria; Vroman, Jeffrey A.; Wu, Baogen; Ager, Arba; Peters, Wallace; Robinson, Brian L.; Charman, William
Journal of Medicinal Chemistry, 2002 , vol. 45, # 19 p. 4321 - 4335
反应条件
dichloro bis(acetonitrile) palladium(II); (Ru2(η5-C5Ph4O)2(H)2(CO)4); water; isopropyl alcohol; p-benozquinone; copper dichloride; tert-butyl alcohol
T=85°C;
参考文献
Dong, Guangbin; Teo, Peili; Wickens, Zachary K.; Grubbs, Robert H.
Science, 2011 , vol. 333, # 6049 p. 1609 - 1612
参考文献
Schadt,F.L. et al.
Journal of the American Chemical Society, 1978 , vol. 100, p. 228 - 246
