1-甲基-1H-吡咯并[2,3-B]吡啶-5-羧酸甲酯合成路线 （共 2 条）
反应条件
1: 1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid With sodium hydride in N,N-dimethyl-formamide; mineral oil
T=0°C; 0.166667 h;
2: methyl iodide in N,N-dimethyl-formamide; mineral oil
T=20°C; 0.5 h;
参考文献
ADVINUS THERAPEUTICS LIMITED; KHARUL, Rajendra; BHUNIYA, Debnath; MOOKHTIAR, Kasim A.; SINGH, Umesh; HAZARE, Atul; PATIL, Satish; DATRANGE, Laxmikant; THAKKAR, Mahesh
Patent: WO2013/42139 A1, 2013 ;
Location in patent: Page/Page column 75 ;
反应条件
lithium hydroxide hydrate; water in tetrahydrofuran; methanol
20 h;
参考文献
ADVINUS THERAPEUTICS LIMITED; KHARUL, Rajendra; BHUNIYA, Debnath; MOOKHTIAR, Kasim A.; SINGH, Umesh; HAZARE, Atul; PATIL, Satish; DATRANGE, Laxmikant; THAKKAR, Mahesh
Patent: WO2013/42139 A1, 2013 ;
Location in patent: Page/Page column 75-76 ;
