2-氯-5-氟-6-氧代-1,6-二氢吡啶-3-羧酸合成路线 (共 1 条)
反应条件
1: With sodium hydroxide in water
T=20°C; 18 h; Heating / reflux;
2: With hydrogenchloride in water
T=0°C; 0.5 h;
参考文献
ARRAY BIOPHARMA INC.; ASTRAZENECA AB
Patent: WO2007/44084 A2, 2007 ;
Location in patent: Page/Page column 134 ;
WO 2007/044084 A2