3-亚甲基氮杂丁烷-1-羧酸苯甲酯合成路线 （共 3 条）
反应条件
1: Methyltriphenylphosphonium bromide With potassium tert-butylate in diethyl ether
T=20 - 35°C; 1.33333 h;
2: N-(Benzyloxycarbonyl)azetidin-3-one in diethyl ether
T=35°C; 12 h;
参考文献
EXELIXIS, INC.
Patent: WO2008/124085 A2, 2008 ;
Location in patent: Page/Page column 179-180 ;
WO 2008/124085 A2
反应条件
1: Methyltriphenylphosphonium bromide With potassium tert-butylate in diethyl ether
T=20 - 35°C; 1.33333 h;
2: N-(Benzyloxycarbonyl)azetidin-3-one in diethyl ether
T=35°C; 12 h;
参考文献
EXELIXIS, INC.
Patent: WO2007/44515 A1, 2007 ;
Location in patent: Page/Page column 165-166 ;
WO 2007/044515 A1
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform
T=0 - 20°C; 12 h;
参考文献
EXELIXIS, INC.
Patent: WO2008/124085 A2, 2008 ;
Location in patent: Page/Page column 180 ;
WO 2008/124085 A2
