N-(3-氨基苯基)丁酰胺合成路线 （共 4 条）
反应条件
hydrogenchloride; hydrogen; iron in water
参考文献
Thiel, W.; Mayer, R.; Jauer, E.-A.; Modrow, H.; Dost, H.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 4 p. 497 - 514
反应条件
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere
2: 5 Pd(II)/C(eggshell); hydrogen / methanol / 16 h
View Scheme
参考文献
Dockendorff, Chris; Aisiku, Omozuanvbo; Verplank, Lynn; Dilks, James R.; Smith, Daniel A.; Gunnink, Susanna F.; Dowal, Louisa; Negri, Joseph; Palmer, Michelle; MacPherson, Lawrence; Schreiber, Stuart L.; Flaumenhaft, Robert
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 3 p. 232 - 237
反应条件
sodium carbonate in water
T=25°C; 10 h; Yield given;
参考文献
Thiel, W.; Mayer, R.; Jauer, E.-A.; Modrow, H.; Dost, H.
Journal fuer Praktische Chemie (Leipzig), 1986 , vol. 328, # 4 p. 497 - 514
反应条件
1: 2-Bromobenzoic acid With oxalyl dichloride; N,N-dimethyl-formamide in dichloromethane
3 h; Inert atmosphereCooling with ice;
2: 3-butyrylaminoaniline With pyridine in dichloromethane
18 h; Inert atmosphere;
参考文献
Dockendorff, Chris; Aisiku, Omozuanvbo; Verplank, Lynn; Dilks, James R.; Smith, Daniel A.; Gunnink, Susanna F.; Dowal, Louisa; Negri, Joseph; Palmer, Michelle; MacPherson, Lawrence; Schreiber, Stuart L.; Flaumenhaft, Robert
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 3 p. 232 - 237
