4-(2-(苄基(6-(4-苯基丁氧基)己基)氨基)-1-羟基乙基)-2-(羟甲基)苯酚合成路线 （共 8 条）
反应条件
hydrogen; palladium on activated charcoal in methanol 10 h;
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
反应条件
sodium tetrahydroborate in methanol
36 h; Ambient temperature;
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
反应条件
1: 81 percent / NaH / tetrahydrofuran / 7 h / Ambient temperature
2: 70 percent / Et3N, NaI / dimethylsulfoxide / 17 h / Ambient temperature
3: 71 percent / acetonitrile / 1 h / Heating; other solvent
4: NaBH4 / methanol / 36 h / Ambient temperature
View Scheme
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
反应条件
1: 81 percent / NaH / tetrahydrofuran / 7 h / Ambient temperature
2: 70 percent / Et3N, NaI / dimethylsulfoxide / 17 h / Ambient temperature
3: 71 percent / acetonitrile / 1 h / Heating; other solvent
4: NaBH4 / methanol / 36 h / Ambient temperature
View Scheme
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
反应条件
1: 66 percent / AlCl3 / CH2Cl2 / 18 h / Heating
2: 71 percent / acetonitrile / 1 h / Heating; other solvent
3: NaBH4 / methanol / 36 h / Ambient temperature
View Scheme
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
反应条件
1: 71 percent / acetonitrile / 1 h / Heating; other solvent
2: NaBH4 / methanol / 36 h / Ambient temperature
View Scheme
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
反应条件
1: 70 percent / Et3N, NaI / dimethylsulfoxide / 17 h / Ambient temperature
2: 71 percent / acetonitrile / 1 h / Heating; other solvent
3: NaBH4 / methanol / 36 h / Ambient temperature
View Scheme
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
反应条件
1: 71 percent / acetonitrile / 1 h / Heating; other solvent
2: NaBH4 / methanol / 36 h / Ambient temperature
View Scheme
参考文献
Rong, Yajing; Ruoho, Arnold E.
Synthetic Communications, 1999 , vol. 29, # 12 p. 2155 - 2162
