2,4-二甲氧苄基异氰酸酯合成路线 (共 3 条)
反应条件
diphenylphosphoranyl azide; triethylamine in toluene
T=20°C; 3.5 h; Heating / reflux;
参考文献
PHARMINOX LIMITED
Patent: WO2009/77741 A2, 2009 ;
Location in patent: Page/Page column 87 ;
反应条件
triethylamine in diethyl ether
T=-78°C; 0.166667 h;
参考文献
Trost, Barry M.; Fandrick, Daniel R.
Organic Letters, 2005 , vol. 7, # 5 p. 823 - 826
反应条件
in toluene
T=100°C; 4 h;
参考文献
Yu; Greig; Holloway; Flippen-Anderson; Brossi
Medicinal Chemistry Research, 2000 , vol. 10, # 3 p. 186 - 199