hydrogen; palladium on activated charcoal in ethyl acetate P=735.5 Torr;

<b>Multi-step reaction with 8 steps<br /> </b>2: 82 percent / H₂ / 10percent Rh/C / ethyl acetate / 735.5 Torr<br />3: 57 percent / trifluoroperacetic acid, disodium hydrogen phosphate / CH₂Cl₂ / 1.) 0 deg C, 1 h; 2.) RT, 30 h<br />4: 80 percent / iodotrimethylsilane / CCl₄ / 5 h / Ambient temperature<br />5: 97 percent / pyridinium chlorochromate; / CH₂Cl₂ / 2.5 h / Ambient temperature<br />6: 87 percent / 25percent NaOMe / methanol / 3.5 h<br />7: t-BuOK / tetrahydrofuran / 63 h / Ambient temperature<br />8: 70 percent / 0.813M BF₃*Et₂O / CH₂Cl₂ / 2 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 97 percent / pyridinium chlorochromate; / CH₂Cl₂ / 2.5 h / Ambient temperature<br />2: 87 percent / 25percent NaOMe / methanol / 3.5 h<br />3: t-BuOK / tetrahydrofuran / 63 h / Ambient temperature<br />4: 70 percent / 0.813M BF₃*Et₂O / CH₂Cl₂ / 2 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 80 percent / iodotrimethylsilane / CCl₄ / 5 h / Ambient temperature<br />2: 97 percent / pyridinium chlorochromate; / CH₂Cl₂ / 2.5 h / Ambient temperature<br />3: 87 percent / 25percent NaOMe / methanol / 3.5 h<br />4: t-BuOK / tetrahydrofuran / 63 h / Ambient temperature<br />5: 70 percent / 0.813M BF₃*Et₂O / CH₂Cl₂ / 2 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 6 steps<br /> </b>1: 57 percent / trifluoroperacetic acid, disodium hydrogen phosphate / CH₂Cl₂ / 1.) 0 deg C, 1 h; 2.) RT, 30 h<br />2: 80 percent / iodotrimethylsilane / CCl₄ / 5 h / Ambient temperature<br />3: 97 percent / pyridinium chlorochromate; / CH₂Cl₂ / 2.5 h / Ambient temperature<br />4: 87 percent / 25percent NaOMe / methanol / 3.5 h<br />5: t-BuOK / tetrahydrofuran / 63 h / Ambient temperature<br />6: 70 percent / 0.813M BF₃*Et₂O / CH₂Cl₂ / 2 h<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '2349612', constants.ctx, '0')">boron trifluoride diethyl etherate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />2&nbsp;h;&nbsp;<br /> &nbsp;