3-(4-吡啶基)-2-丙炔-1-醇合成路线 （共 5 条）
反应条件
palladium on activated charcoal; hydrogen; acetic acid in methanol T=20°C;
参考文献
Shaghafi, Michael B.; Barrett, David G.; Willard, Francis S.; Overman, Larry E.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 4 p. 1031 - 1036
反应条件
1: hydrogen; palladium on activated charcoal; acetic acid / methanol / 20 °C 2: Dess-Martin periodane / dichloromethane / 20 °C View Scheme
参考文献
Shaghafi, Michael B.; Barrett, David G.; Willard, Francis S.; Overman, Larry E.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 4 p. 1031 - 1036
反应条件
copper(l) iodide; potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)); Tedicyp in N,N-dimethyl-formamide
T=100°C; 20 h;
参考文献
Feuerstein, Marie; Doucet, Henri; Santelli, Maurice
Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1717 - 1720
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine
Sonogashira coupling;
参考文献
Wessig, Pablo; Pick, Charlotte
Journal of Photochemistry and Photobiology A: Chemistry, 2011 , vol. 222, # 1 p. 263 - 265
反应条件
copper(l) iodide; potassium carbonate; bis(η3-allyl-μ-chloropalladium(II)); Tedicyp in N,N-dimethyl-formamide
T=100°C; 20 h;
参考文献
Feuerstein, Marie; Doucet, Henri; Santelli, Maurice
Tetrahedron Letters, 2005 , vol. 46, # 10 p. 1717 - 1720
