triethylamine in dichloromethane 5 h; Ambient temperature;

1: sodium cyanide With ammonia in water T=25°C; P=1125.11 Torr; 0.5 h; 2: phenylacetaldehyde With acetic acid in water T=35°C; 4.75 h; 3: With hydrogenchloride in 1,4-dioxane; diethyl ether

1: phenylacetaldehyde With sodium hydrogensulfite in tetrahydrofuran; water 0.333333 h; 2: With ammonium hydroxide in tetrahydrofuran; water T=60°C; 1 h; 3: sodium cyanide in tetrahydrofuran; water T=0 - 30°C; 2 h;

ammonium chloride in 1,4-dioxane; water 48 h; Ambient temperature;

ammonia in methanol T=40°C; 2 h; Yield given;

1: zinc iodide / neat (no solvent) / 0.25 h 2: ammonia / methanol / 2 h / 40 °C View Scheme

1: 94 percent / pyridine; TiCl4 / 0.5 h / 20 °C 2: 95 percent / Zn; AcOH / CH2Cl2; methanol / 0.33 h / Heating View Scheme

1: With sodium hydroxide; iron(III) chloride in methanol 4 h; Heating; 2: With hydrogen; palladium on activated charcoal T=50°C; P=3800 Torr; 18 h;

1: 69 percent / hydroxybenzotriazole; EDC; pyridine / CH2Cl2 / 15 h / 20 °C 2: CH2Cl2 / 1.5 h / 0 °C 3: NH2OH*HCl; Na2CO3 / ethanol; H2O / 19 h / 20 - 70 °C 4: H2 / Raney-Ni W2 / methanol / 3 h / 20 °C / atmospheric pressure 5: pyridine / 1 h / 20 °C 6: 91 percent / NaH / tetrahydrofuran / 2 h / 20 °C 7: 85 percent / i-Pr2NEt / CH2Cl2 / 2 h / 0 °C 8: 85 percent / K3PO4*3H2O; Pd(PPh3)4 / dioxane / 1.5 h / 80 °C 9: 38 percent / H2SO4 / 0.17 h / 0 °C View Scheme

triethylamine in dichloromethane 5 h; Ambient temperature;