反应条件
1.1: CuCN*2LiCl / tetrahydrofuran / 0.5 h / 0 °C
1.2: 66 percent / tetrahydrofuran / 25 °C
2.1: n-BuLi / tetrahydrofuran; pentane / 0.5 h / -78 °C
2.2: B(OMe)3 / tetrahydrofuran; pentane / 24 h / -78 - 25 °C
2.3: 45 percent / NaBO3*4H2O / tetrahydrofuran; pentane / 24 h / 25 °C
3.1: p-TsOH / benzene / 12 h / 25 °C
4.1: TBAF / tetrahydrofuran / 16 h / 25 °C
5.1: 17 mg / Celite; CrO3 / diethyl ether; CH2Cl2 / 12 h / 25 °C
View Scheme
参考文献
Soorukram, Darunee; Knochel, Paul
Organic Letters, 2007 , vol. 9, # 6 p. 1021 - 1023
