3-氟-5-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)苯甲腈合成路线 (共 2 条)
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in 1,4-dioxane; dichloromethane; dimethyl sulfoxide
T=90°C; Inert atmosphere;
参考文献
AiCuris GmbH and Co. KG; Thede, Kai; Greschat, Susanne; Gericke, Kersten Matthias; Wildum, Steffen; Paulsen, Daniela
Patent: US2013/45999 A1, 2013 ;
Location in patent: Paragraph 0224; 0225; 0226; 0227 ;
反应条件
potassium carbonate; bis-triphenylphosphine-palladium(II) chloride in ethylene glycol dimethyl ether; water
T=20 - 80°C;
参考文献
Cosford, Nicholas D.; Seiders, Thomas J.; Payne, Joseph; Roppe, Jeffrey R.; Huang, Dehua; Smith, Nicholas D.; Poon, Steve F.; King, Chris; Eastman, Brian W.; Wang, Bowei; Arruda, Jeannie M.; Vernier, Jean-Michel; Zhao, Xiumin
Patent: US2009/203903 A1, 2009 ;
Location in patent: Page/Page column 9 ;
US 20090203903 A1