1-(4-甲氧基苯基)吲哚合成路线 （共 15 条）
反应条件
potassium phosphate; tris(dibenzylideneacetone)dipalladium (0); N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine in toluene
T=100°C; Arylation;
参考文献
Old, David W.; Harris, Michele C.; Buchwald, Stephen L.
Organic Letters, 2000 , vol. 2, # 10 p. 1403 - 1406
反应条件
sodium hydride; 1-n-butyl-3-methylimidazolium tetrafluoroborate
T=40°C;
参考文献
Wang, Feng-Yan; Chen, Zhen-Chu; Zheng, Qin-Guo
Journal of Chemical Research, 2004 , # 3 p. 206 - 207
反应条件
1.1: n-BuLi / tetrahydrofuran; hexane / 2 h / -78 °C
1.2: 85 percent / tetrahydrofuran; hexane / -78 - 20 °C
2.1: 50 percent / 2-(di-tert-butylphosphino)-2'-(isopropyl)biphenyl; Cs2CO3; KF / Pd(OAc)2; scCO2 / 17 h / 100 °C / 93086.6 Torr
View Scheme
参考文献
Smith, Catherine J.; Tsang, Melanie W.S.; Holmes, Andrew B.; Danheiser, Rick L.; Tester, Jefferson W.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 20 p. 3767 - 3781
反应条件
copper(l) iodide; potassium carbonate in dimethyl sulfoxide
T=80°C; 63 h;
参考文献
Ma, Dawei; Cai, Qian
Synlett, 2004 , # 1 p. 128 - 130
反应条件
1: tris-(dibenzylideneacetone)dipalladium(0); 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; sodium tert-pentoxide / 1,4-dioxane / 12 h / 110 °C / |Inert atmosphere
2: Ru(bpz)3(PF6)2 / acetonitrile / 12 h / 20 °C / |Irradiation; |Inert atmosphere
View Scheme
参考文献
Maity, Soumitra; Zheng, Nan
Angewandte Chemie - International Edition, 2012 , vol. 51, # 38 p. 9562 - 9566
