2-甲基吡咯-3-甲酸乙酯合成路线 （共 28 条）
反应条件
1: 75 percent / methanol / 12 h / 20 °C 2: 68 percent / DIBAL-H / tetrahydrofuran / 1 h / -20 °C View Scheme
参考文献
Tetrahedron, , vol. 55, # 21 p. 6555 - 6566
反应条件
1: With ammonium hydroxide in water 2: With hydrogenchloride in diethyl ether; water
参考文献
Skaddan, Marc B.
Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 2 p. 73 - 77
反应条件
1: 92 percent / DDQ / benzene / 48 h / Ambient temperature 2: 98 percent / 5 N NaOH / methanol / 0.25 h View Scheme
参考文献
Liebigs Annalen der Chemie, , # 4 p. 529 - 534
反应条件
sodium amalgam; ethanol unter Kuehlung und Behandeln der Reaktionsloesung mit Acetessigsaeure-aethylester und wss. NaOH oder wss. KOH;
参考文献
Gazzetta Chimica Italiana, , vol. 86, p. 757,762
Bulletin of the Chemical Society of Japan, , vol. 12, p. 316
反应条件
bromine Behandeln des Reaktionsprodukts mit Acetessigsaeure-aethylester und wss. NH3;
参考文献
Justus Liebigs Annalen der Chemie, , vol. 615, p. 137,163
反应条件
ammonium acetate; mercury dichloride further solvents and temperatures; 1) MeCN, H2O, reflux, 24 h; 2) MeCN, H2O, room temperature, overnight; Yield given. Multistep reaction;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 17 p. 2355 - 2356
参考文献
Gazzetta Chimica Italiana, , vol. 89, p. 1457,1458
参考文献
Chemische Berichte, , vol. 44, p. 490
Chemische Berichte, , vol. 51, p. 569
参考文献
Chemische Berichte, , vol. 44, p. 490
Chemische Berichte, , vol. 51, p. 569
反应条件
sodium hydroxide; hydrazine hydrate; ethylene glycol T=170°C;
参考文献
Treibs; Schmidt
Justus Liebigs Annalen der Chemie, 1952 , vol. 577, p. 105,111
