(3,5-二-叔丁基-4-甲氧基-苯基)-甲醇合成路线 （共 8 条）
反应条件
methanol; potassium borohydride in tetrahydrofuran
T=50°C; 24 h;
参考文献
Shanahan, Charles S.; McGrath, Dominic V.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1054 - 1056
反应条件
1: t-BuOK / acetonitrile / 36 h / 80 °C
2: NaBH4; NaOH / propan-2-ol
View Scheme
参考文献
D'Acunzo, Francesca; Galli, Carlo; Gentili, Patrizia; Sergi, Federica
New Journal of Chemistry, 2006 , vol. 30, # 4 p. 583 - 591
反应条件
1: 93 percent / NBS; DMSO
2: p-toluenesulfonic acid / benzene / 48 h / Heating
3: K2CO3 / 18-crown-6 / acetone; dimethylformamide / 48 h / Heating
4: HCl / acetone / 40 °C
5: KBH4; MeOH / tetrahydrofuran / 24 h / 50 °C
View Scheme
参考文献
Shanahan, Charles S.; McGrath, Dominic V.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1054 - 1056
反应条件
1: K2CO3 / 18-crown-6 / acetone; dimethylformamide / 48 h / Heating
2: HCl / acetone / 40 °C
3: KBH4; MeOH / tetrahydrofuran / 24 h / 50 °C
View Scheme
参考文献
Shanahan, Charles S.; McGrath, Dominic V.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1054 - 1056
反应条件
sodium methylate in methanol
18 h; Ambient temperature;
参考文献
Campi, Eva M.; Gatehouse, Bryan M. K.; Jackson, W. Roy; Rae, Ian D.; Wong, Margaret G.
Canadian Journal of Chemistry, 1984 , vol. 62, p. 2566 - 2569
反应条件
1: 98 percent / laccase; oxygen; TEMPO / acidic aq. solution / 24 h / 20 °C / pH 5
2: t-BuOK / acetonitrile / 36 h / 80 °C
3: NaBH4; NaOH / propan-2-ol
View Scheme
参考文献
D'Acunzo, Francesca; Galli, Carlo; Gentili, Patrizia; Sergi, Federica
New Journal of Chemistry, 2006 , vol. 30, # 4 p. 583 - 591
反应条件
1: 62 percent / N-bromosuccinimide, benzoyl peroxide / CCl4 / 18 h / Heating; Irradiation
2: 11.2 g / acetic acid / 9 h / Heating
3: 59 percent / sodium methoxide / methanol / 18 h / Ambient temperature
View Scheme
参考文献
Campi, Eva M.; Gatehouse, Bryan M. K.; Jackson, W. Roy; Rae, Ian D.; Wong, Margaret G.
Canadian Journal of Chemistry, 1984 , vol. 62, p. 2566 - 2569
反应条件
1: 11.2 g / acetic acid / 9 h / Heating
2: 59 percent / sodium methoxide / methanol / 18 h / Ambient temperature
View Scheme
参考文献
Campi, Eva M.; Gatehouse, Bryan M. K.; Jackson, W. Roy; Rae, Ian D.; Wong, Margaret G.
Canadian Journal of Chemistry, 1984 , vol. 62, p. 2566 - 2569
