(S)-3-氨基-3-苯基-1-丙醇盐酸盐合成路线 （共 5 条）
反应条件
triethylamine in dichloromethane T=20°C; 1 h;
参考文献
US2013/345126 A1, ;
Paragraph 0359-0360 ;
反应条件
hydrogenchloride
Heating;
参考文献
Fadnavis, Nitin W.; Radhika, Kasiraman R.; Vedamayee Devi
Tetrahedron Asymmetry, 2006 , vol. 17, # 2 p. 240 - 244
反应条件
1: 47.5 percent / penicillin G acylase immobilized on epoxy-resin; phosphate buffer / ethanol; H2O / 1 h / 25 °C / pH 7.5
2: 100 percent / aq. HCl / Heating
View Scheme
参考文献
Fadnavis, Nitin W.; Radhika, Kasiraman R.; Vedamayee Devi
Tetrahedron Asymmetry, 2006 , vol. 17, # 2 p. 240 - 244
反应条件
1: 90 percent / Saccharomyces cerevisiae; glucose; phenacyl chloride / aq. phosphate buffer; diisopropyl ether / 48 h / 20 °C / pH 4.5
2: 65 percent / ammonium acetate; sodium cyanoborohydride / ethanol / 36 h / 20 °C
3: 80 percent / aq. NaOH / 4 h / 20 °C
4: 47.5 percent / penicillin G acylase immobilized on epoxy-resin; phosphate buffer / ethanol; H2O / 1 h / 25 °C / pH 7.5
5: 100 percent / aq. HCl / Heating
View Scheme
参考文献
Fadnavis, Nitin W.; Radhika, Kasiraman R.; Vedamayee Devi
Tetrahedron Asymmetry, 2006 , vol. 17, # 2 p. 240 - 244
反应条件
1: 80 percent / aq. NaOH / 4 h / 20 °C
2: 47.5 percent / penicillin G acylase immobilized on epoxy-resin; phosphate buffer / ethanol; H2O / 1 h / 25 °C / pH 7.5
3: 100 percent / aq. HCl / Heating
View Scheme
参考文献
Fadnavis, Nitin W.; Radhika, Kasiraman R.; Vedamayee Devi
Tetrahedron Asymmetry, 2006 , vol. 17, # 2 p. 240 - 244
