2-叔丁基-1-甲基-4-(三甲基锡烷基)-1H-咪唑合成路线 (共 1 条)
反应条件
1: 1-methyl-4-iodo-2-tert-butylimidazole With ethylmagnesium bromide in diethyl ether; dichloromethane
T=20°C; 1 h;
2: trimethylstannyl chloride in diethyl ether; dichloromethane
T=20°C; 16.0833 h;
参考文献
CYTOKINETICS, INC.; SMITHKLINE BEECHAM CORPORATION
Patent: WO2007/56143 A2, 2007 ;
Location in patent: Page/Page column 62 ;