5-溴-1H-吡咯-2-羧酸甲酯合成路线 （共 7 条）
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide T=0 - 18°C; 16 h;
参考文献
Banwell, Martin G.; Hamel, Ernest; Hockless, David C.R.; Verdier-Pinard, Pascal; Willis, Anthony C.; Wong, David J.
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 13 p. 4627 - 4638
反应条件
2-(n-morpholino)ethanesulfonic acid; VBrPO(AnI) bromoperoxidase; dihydrogen peroxide; sodium bromide in water; tert-butyl alcohol T=20°C; pH=6.2; ConcentrationReagent/catalyst;
参考文献
Wischang, Diana; Radlow, Madlen; Hartung, Jens
Dalton Transactions, 2013 , vol. 42, # 33 p. 11926 - 11940
反应条件
sodium tetrahydroborate in tetrahydrofuran T=-78°C; 1.75 h;
参考文献
Organic Letters, , vol. 8, # 14 p. 2961 - 2964
反应条件
bromine in water; tert-butyl alcohol T=25°C; regioselective reaction;
参考文献
Tetrahedron, , vol. 67, # 22 p. 4048 - 4054
反应条件
1: methanol / 0.67 h / 23 °C / Inert atmosphere 2: Ascophyllum nodosum vanadate(V)-dependent bromoperoxidase I; dihydrogen peroxide; sodium bromide / water; tert-butyl alcohol / 24 h / 23 °C / pH 6.2 / aq. buffer; Enzymatic reaction View Scheme
参考文献
Tetrahedron, , vol. 67, # 22 p. 4048 - 4054
反应条件
1: methanol / 0.67 h / 23 °C / Inert atmosphere 2: bromine / water; tert-butyl alcohol / 25 °C View Scheme
参考文献
Tetrahedron, , vol. 67, # 22 p. 4048 - 4054
反应条件
1: methanol / 0.67 h / 23 °C / Inert atmosphere 2: Ascophyllum nodosum vanadate(V)-dependent bromoperoxidase I; dihydrogen peroxide; sodium bromide / water; tert-butyl alcohol / 24 h / 23 °C / pH 6.2 / aq. buffer; Enzymatic reaction View Scheme
参考文献
Tetrahedron, , vol. 67, # 22 p. 4048 - 4054
