N-(噻唑-2-甲基)甲酰胺合成路线 （共 3 条）
反应条件
1: With trichlorophosphate T=60°C; 3.5 h; 2: With sodium hydroxide in water
参考文献
MERCK SHARP and DOHME CORP.; MACHACEK, Michelle, R.; AHEARN, Sean, P.; ROMEO, Eric; SIU, Tony; CHICHETTI, Stephanie; DE ALMEIDA, Gabriela
Patent: WO2011/37780 A1, 2011 ;
Location in patent: Page/Page column 53-54 ;
WO 2011/037780 A1
反应条件
in toluene
3 h; Heating;
参考文献
De Lazlo,S.E.; Willard,P.G.
Journal of the American Chemical Society, 1985 , vol. 107, p. 199
反应条件
N-ethyl-N,N-diisopropylamine
T=60°C;
参考文献
MERCK SHARP and DOHME CORP.; MACHACEK, Michelle, R.; AHEARN, Sean, P.; ROMEO, Eric; SIU, Tony; CHICHETTI, Stephanie; DE ALMEIDA, Gabriela
Patent: WO2011/37780 A1, 2011 ;
Location in patent: Page/Page column 53-54 ;
WO 2011/037780 A1
