1-(7-溴-3,4-二氢异喹啉-2(1h)-基)乙酮合成路线 （共 3 条）
反应条件
triethylamine in dichloromethane
T=0°C; 2 h;
参考文献
F. HOFFMANN-LA ROCHE AG; HERMANN, Johannes Cornelius; KUGLSTATTER, Andreas; LUCAS, Matthew C.; PADILLA, Fernando; WANNER, Jutta; ZHANG, Xiaohu
Patent: WO2013/64445 A1, 2013 ;
Location in patent: Page/Page column 128-129 ;
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane
T=0 - 20°C; 15 h;
参考文献
ASTRAZENECA AB; ASTEX THERAPEUTICS LTD
Patent: WO2007/58602 A2, 2007 ;
Location in patent: Page/Page column 77 ;
WO 2007/058602 A2
反应条件
potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in ethylene glycol dimethyl ether
T=150°C; 0.25 h; Microwave;
参考文献
ASTRAZENECA AB; ASTEX THERAPEUTICS LTD
Patent: WO2007/58602 A2, 2007 ;
Location in patent: Page/Page column 77-78 ;
WO 2007/058602 A2
