5’-O-[双(4-甲氧基苯基)苯基甲基]-2’-脱氧肌苷合成路线 （共 7 条）
反应条件
lithium carbonate; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=20°C; Heating;
参考文献
Hansen, Anders S.; Thalhammer, Armin; El-Sagheer, Afaf H.; Brown, Tom; Schofield, Christopher J.
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 4 p. 1181 - 1184
参考文献
Zeidler, Joanna; Golankiewicz, Bozenna
Nucleosides and Nucleotides, 1996 , vol. 15, # 5 p. 1077 - 1095
反应条件
1: tetrafluoroboric acid / water / 0.67 h / Cooling with ice 2: lithium carbonate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1181 - 1184
反应条件
1: sodium hydroxide / tetrahydrofuran; water / 1.5 h / 20 °C 2: 80 °C / Cooling with ice 3: tetrafluoroboric acid / water / 0.67 h / Cooling with ice 4: lithium carbonate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1181 - 1184
反应条件
1: 80 °C / Cooling with ice 2: tetrafluoroboric acid / water / 0.67 h / Cooling with ice 3: lithium carbonate; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 4 p. 1181 - 1184
反应条件
1: dimethylformamide / 20 h 2: 84 percent / tri-n-butyltin hydride, azobisisobutyronitrile / dioxane / 1 h / Heating 3: 65 percent / aq. AcOH / 1.5 h / 0 °C View Scheme
参考文献
Nucleosides and Nucleotides, , vol. 15, # 5 p. 1077 - 1095
反应条件
1: dimethylformamide / 20 h 2: 84 percent / tri-n-butyltin hydride, azobisisobutyronitrile / dioxane / 1 h / Heating 3: 65 percent / aq. AcOH / 1.5 h / 0 °C 4: 89 percent / pyridine / overnight View Scheme
参考文献
Zeidler, Joanna; Golankiewicz, Bozenna
Nucleosides and Nucleotides, 1996 , vol. 15, # 5 p. 1077 - 1095
