4-Hydroxy-2-methoxy-6-methylbenzoesaeure-methylester; potassium carbonate; copper(II) oxide T=140°C; 16 h;

potassium carbonate; copper(II) oxide T=140°C; 16 h;

hydrogen; palladium on activated charcoal 1.) ethanol, 18 h; Multistep reaction;

1: 75 percent / potassium carbonate, copper(II) oxide / 16 h / 140 °C 2: 90 percent / bromine / CH2Cl2 / 0.25 h 3: 69 percent / tin(II) chloride dihydrate, hydrochloric acid / methanol / 4 h / Heating 4: 1.) isopentyl nitrite, 2.) copper(II) bromide / 1.) acetonitrile 5: 48 percent / copper bronze / 2 h / 260 °C 6: 98 percent / potassium hydroxide, water / dimethylsulfoxide / 1.67 h / Heating 7: 11 percent / copper chromite / quinoline / 1.5 h / 180 °C View Scheme