3,4-二甲基-1H-吡咯-2-羧酸乙酯合成路线 （共 34 条）
反应条件
toluene-4-sulfonic acid in benzene
0.5 h; Heating;
参考文献
Moon, M. W.; Wade, R. A.
Journal of Organic Chemistry, 1984 , vol. 49, # 15 p. 2663 - 2669
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in various solvent(s)
T=20°C; Barton-Zard pyrrole synthesis;
参考文献
Bhattacharya, Apurba; Cherukuri, Sankara; Plata, Robert Erik; Patel, Nitinchandra; Tamez Jr., Victoriano; Grosso, John A.; Peddicord, Michael; Palaniswamy, Venkatapuram A.
Tetrahedron Letters, 2006 , vol. 47, # 31 p. 5481 - 5484
反应条件
in acetonitrile; benzene
6 h; Irradiation;
参考文献
D'Auria, Maurizio; De Luca, Eliana; Mauriello, Giacomo; Racioppi, Rocco; Sleiter, Giancarlo
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 16 p. 2369 - 2373
反应条件
sodium acetate; acetic acid; zinc
T=95 - 105°C; 0.5 h;
参考文献
Byun; Lightner
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 7 p. 1683 - 1692
反应条件
sodium acetate; acetic acid; zinc
2 h; Heating;
参考文献
Xie, Meiqiang; Lightner, David A.
Tetrahedron, 1993 , vol. 49, # 11 p. 2185 - 2200
反应条件
1: (i-Pr)2NEt / toluene / 0 °C
2: 1 h / 0 °C
View Scheme
参考文献
D'Auria, Maurizio; De Luca, Eliana; Mauriello, Giacomo; Racioppi, Rocco; Sleiter, Giancarlo
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 16 p. 2369 - 2373
反应条件
1: KOH / methanol / 2 h / Heating
2: (i-Pr)2NEt / toluene / 0 °C
3: 1 h / 0 °C
View Scheme
参考文献
D'Auria, Maurizio; De Luca, Eliana; Mauriello, Giacomo; Racioppi, Rocco; Sleiter, Giancarlo
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 16 p. 2369 - 2373
反应条件
1: 1.) SOCl2, pyridine / 1.) C6H6, r.t., 1 h, 2.) reflux, overnight
2: KOH / methanol / 2 h / Heating
3: (i-Pr)2NEt / toluene / 0 °C
4: 1 h / 0 °C
View Scheme
参考文献
D'Auria, Maurizio; De Luca, Eliana; Mauriello, Giacomo; Racioppi, Rocco; Sleiter, Giancarlo
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 16 p. 2369 - 2373
参考文献
Fischer; Hoefelmann
Justus Liebigs Annalen der Chemie, 1938 , vol. 533, p. 216,229
反应条件
1: SO2Cl2; diethyl ether / Erwaermen des Reaktionsprodukts mit H2O
2: 220 °C
View Scheme
参考文献
Siedel
Justus Liebigs Annalen der Chemie, 1943 , vol. 554, p. 144,159
