3,4-二甲基-1H-吡咯-2-羧酸乙酯合成路线 （共 34 条）
反应条件
sulfuryl dichloride
1.) CCl4, cooling, overnight, 2.) reflux, 15 min; Yield given. Multistep reaction;
参考文献
Scarsella, Marco; Sleiter, Giancarlo
Gazzetta Chimica Italiana, 1988 , vol. 118, # 11 p. 757 - 762
反应条件
hydrogenchloride in dichloromethane
T=60°C; 96 h; further solvent, reagent, time; MechanismProduct distribution;
参考文献
Giuliano, Francesco; Penna, Marina; Sleiter, Giancarlo
Gazzetta Chimica Italiana, 1986 , vol. 116, # 10 p. 589 - 594
反应条件
1: Raney nickel; ethanol / 160 °C / 110326 Torr / Hydrogenation
2: SO2Cl2; diethyl ether / Erwaermen des Reaktionsprodukts mit H2O
3: 250 °C
View Scheme
参考文献
Fischer; Hoefelmann
Justus Liebigs Annalen der Chemie, 1938 , vol. 533, p. 216,229
参考文献
Datta, Suchitra; Lightner, David A.
Monatshefte fur Chemie, 2008 , vol. 139, # 9 p. 1113 - 1117
反应条件
T=0°C; 1 h; Yield given;
参考文献
D'Auria, Maurizio; De Luca, Eliana; Mauriello, Giacomo; Racioppi, Rocco; Sleiter, Giancarlo
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 16 p. 2369 - 2373
参考文献
D'Auria, Maurizio; De Luca, Eliana; Mauriello, Giacomo; Racioppi, Rocco; Sleiter, Giancarlo
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 16 p. 2369 - 2373
反应条件
N-ethyl-N,N-diisopropylamine
1.) toluene, 0 deg C, overnight, 2.) 0 degC - 5 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Scarsella, Marco; Sleiter, Giancarlo
Gazzetta Chimica Italiana, 1988 , vol. 118, # 11 p. 757 - 762
反应条件
Yield given. Multistep reaction;
参考文献
Giuliano, Francesco; Penna, Marina; Sleiter, Giancarlo
Gazzetta Chimica Italiana, 1986 , vol. 116, # 10 p. 589 - 594
反应条件
tin(IV) chloride in dichloromethane
0.25 h; Ambient temperature;
参考文献
Sessler, Jonathan L.; Weghorn, Steven J.; Hiseada, Yoshio; Lynch, Vincent
Chemistry--A European Journal, 1995 , vol. 1, # 1 p. 56 - 67
反应条件
tin(IV) chloride in dichloromethane
1.) 0 deg C, 5 min, in the dark, 2.) 10 min;
参考文献
Xie, Hong; Lee, David A.; Wallace, David M.; Senge, Mathias O.; Smith, Kevin M.
Journal of Organic Chemistry, 1996 , vol. 61, # 24 p. 8508 - 8517
