3,4-二甲基-1H-吡咯-2-羧酸乙酯合成路线 （共 34 条）
反应条件
diethyl ether; ethylmagnesium bromide
参考文献
Fischer; Hoefelmann
Justus Liebigs Annalen der Chemie, 1938 , vol. 533, p. 216,229
反应条件
titanium(IV) isopropylate
P=15 Torr; 15 h; Heating;
参考文献
Zindel; Lightner
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 4 p. 1219 - 1223
反应条件
iodine; potassium carbonate in methanol
1.) r.t., 2 h, 2.) 0 deg C, overnight;
参考文献
D'Auria, Maurizio; De Luca, Eliana; Mauriello, Giacomo; Racioppi, Rocco; Sleiter, Giancarlo
Journal of the Chemical Society - Perkin Transactions 1, 1997 , # 16 p. 2369 - 2373
反应条件
1: 100 percent / NaOH / ethanol; H2O / 16 h / Heating
2: 65 percent / H2O / Heating
3: 95 percent / H2O2; pyridine / methanol / Heating
View Scheme
参考文献
Chen, Qingqi; Wang, Tianyu; Zhang, Yi; Wang, Qiuan; Ma, Jinshi
Synthetic Communications, 2002 , vol. 32, # 7 p. 1031 - 1040
