2-(4-甲基苯基)丙酸合成路线 （共 38 条）
反应条件
1: 4-methyl-styrene With (C5H3N)(MeC=N(C6H4-2,6-iPr2))2; ethylmagnesium bromide; iron(II) chloride in tetrahydrofuran; diethyl ether T=20°C; 2 h; Inert atmosphere; 2: carbon dioxide in tetrahydrofuran; diethyl ether 0.5 h; Inert atmosphere; regioselective reaction;
参考文献
Greenhalgh, Mark D.; Thomas, Stephen P.
Journal of the American Chemical Society, 2012 , vol. 134, # 29 p. 11900 - 11903
反应条件
sodium hydroxide in water Heating;
参考文献
Uemura, Sakae; Fukuzawa, Shin-ichi; Yamauchi, Takayoshi; Hattori, Kaneaki; Mizutaki, Shoichi; Tamaki, Kentaro
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1983 - 1987
反应条件
water; hydrogen iodide T=90°C; 20 h;
参考文献
Aramini, Andrea; Sablone, Manolo R.; Bianchini, Gianluca; Amore, Alessia; Fani, Michela; Perrone, Plinio; Dolce, Alberto; Allegretti, Marcello
Tetrahedron, 2009 , vol. 65, # 10 p. 2015 - 2021
反应条件
lithium aluminium tetrahydride; titanium tetrachloride in tetrahydrofuran T=-5°C; 0.5 h;
参考文献
Garcia, Mariano; Del Campo, Carmen; Sinisterra, Jose V.; Llama, Emilio F.
Tetrahedron Letters, 1993 , vol. 34, # 49 p. 7973 - 7974
反应条件
water; methyloxirane in acetone 3 h; Irradiation;
参考文献
Sonawane, Harikisan R.; Kulkarni, Dilip G.; Ayyangar, Nagaraj R.
Tetrahedron Letters, 1990 , vol. 31, # 51 p. 7495 - 7496
反应条件
1: potassium tert-butoxide / hexane / 0.5 h / Ambient temperature 2: 85percent formic acid / 10percent Pd/C / hexane / 6 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 49, # 37 p. 8433 - 8440
反应条件
ruthenium trichloride; sodium periodate in hexane; water; ethyl acetate T=20°C; 24 h; chemoselective reaction;
参考文献
Synthesis, , # 23 art. no. F16908SS, p. 3835 - 3845
反应条件
potassium permanganate; sulfuric acid
参考文献
Journal of the American Chemical Society, , vol. 83, p. 1196 - 1213
反应条件
methyloxirane in water; acetone IrradiationpH neutral;
参考文献
Tetrahedron, , vol. 50, # 4 p. 1243 - 1260
反应条件
1: AlCl3 2: 84 percent / propylene oxide / H2O; acetone / Irradiation; pH neutral View Scheme
参考文献
Tetrahedron, , vol. 50, # 4 p. 1243 - 1260
