N-(对氨基苯乙基)螺哌隆合成路线 （共 4 条）
反应条件
hydrogenchloride; iron in ethanol
30 h;
参考文献
Bakthavachalam, Venkatesalu; Baindur, Nandkishore; Madras, Bertha K.; Neumeyer, John L.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 11 p. 3235 - 3241
反应条件
trifluoroacetic acid in dichloromethane
T=20°C; 2 h;
参考文献
Jin, Chunyang; Mayer, Louise D.; Lewin, Anita H.; Rehder, Kenneth S.; Brine, George A.
Synthetic Communications, 2008 , vol. 38, # 5 p. 816 - 823
反应条件
1: 1.3 g / KOH, K2CO3, (n-Bu)4NHSO4 / toluene / 2 h / 90 °C
2: 53 percent / conc. aq. HCl, Fe / ethanol / 30 h
View Scheme
参考文献
Bakthavachalam, Venkatesalu; Baindur, Nandkishore; Madras, Bertha K.; Neumeyer, John L.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 11 p. 3235 - 3241
反应条件
1: 1.3 g / KOH, K2CO3, (n-Bu)4NHSO4 / toluene / 2 h / 90 °C
2: 53 percent / conc. aq. HCl, Fe / ethanol / 30 h
View Scheme
参考文献
Bakthavachalam, Venkatesalu; Baindur, Nandkishore; Madras, Bertha K.; Neumeyer, John L.
Journal of Medicinal Chemistry, 1991 , vol. 34, # 11 p. 3235 - 3241
