1: lithium diethylamide / ethylene glycol dimethyl ether / 2.42 h / -45 °C / |Inert atmosphere 2: bromine / ethylene glycol dimethyl ether / 4.5 h / 10 - 45 °C / |Inert atmosphere 3: sodium carbonate / water; ethylene glycol dimethyl ether / 6 h / 55 °C / |Inert atmosphere View Scheme

lithium diethylamide in ethylene glycol dimethyl ether T=-45°C; 2.41667 h; Inert atmosphere;