aluminium amalgam in tetrahydrofuran; water T=80°C; 2 h;

<b>Multi-step reaction with 4 steps<br /> </b>1: methanol / 3 h / Ambient temperature<br />2: MCPBA<br />4: 56 percent / 1) Me₃SiI, 2)MeOH / 168 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 1) Me₃SiI, 2) MeOH / 1)CDCl₃, 6 d<br />2: 24 percent / Raney Ni / acetone<br />3: 60 percent / n-BuLi / tetrahydrofuran / 2 h / 65 &deg;C<br />4: MCPBA / CH₂Cl₂ <br />5: 56 percent / 1) Me₃SiI, 2)MeOH / 168 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: MCPBA / CH₂Cl₂ <br />2: 56 percent / 1) Me₃SiI, 2)MeOH / 168 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 60 percent / n-BuLi / tetrahydrofuran / 2 h / 65 &deg;C<br />2: MCPBA / CH₂Cl₂ <br />3: 56 percent / 1) Me₃SiI, 2)MeOH / 168 h<br /> <br /> &nbsp;