2-氰基-6-羟基苯并噻唑合成路线 （共 26 条）
反应条件
in methanol; hexane; ethyl acetate
参考文献
Board of Governors of Wayne State University
Patent: US5616729 A1, 1997 ;
反应条件
trimethylsilyl iodide in diethyl ether; chloroform; dimethyl sulfoxide
参考文献
Boehringer Mannheim GmbH
Patent: US4826989 A1, 1989 ;
反应条件
sodium tetrahydroborate; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=20°C; 24 h; Inert atmosphere;
参考文献
Meroni, Giuseppe; Ciana, Paolo; Maggi, Adriana; Santaniello, Enzo
Synlett, 2009 , # 16 p. 2682 - 2684
反应条件
1: (i) P2S5, xylene, (ii) K3<Fe(CN)6>, aq. NaOH 2: HCl 3: NH3 / methanol 4: POCl3 5: Py*HCl / 200 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 85, p. 337 - 343
反应条件
1: HCl 2: NH3 / methanol 3: POCl3 4: Py*HCl / 200 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 85, p. 337 - 343
反应条件
pyridine hydrochloride T=185 - 195°C; 2 h;
参考文献
Journal of the American Chemical Society, , vol. 85, p. 337 - 343
反应条件
1: dimethylsulfoxide / 2.5 h / 125 °C 2: Py*HCl / 2 h / 185 - 195 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 85, p. 337 - 343
反应条件
1: NH3 / methanol 2: POCl3 3: Py*HCl / 200 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 85, p. 337 - 343
反应条件
1: POCl3 2: Py*HCl / 200 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 85, p. 337 - 343
反应条件
1: copper(l) iodide; tetrabutylammomium bromide; palladium dichloride / dimethyl sulfoxide; N,N-dimethyl-formamide / 3 h / 120 °C / Inert atmosphere 2: pyridine hydrochloride / 1 h / 180 °C / Neat (no solvent); Inert atmosphere View Scheme
参考文献
Journal of the American Chemical Society, , vol. 134, # 18 p. 7604 - 7607
