2-氰基-6-羟基苯并噻唑合成路线 （共 26 条）
反应条件
(i) Na, liq. NH3, (ii) /BRN= 744134/, aq. MeOH; Multistep reaction;
参考文献
White,E.H. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 337 - 343
反应条件
1: (i) Na, liq. NH3, (ii) /BRN= 744134/, aq. MeOH
2: aq. NaOH / Heating
View Scheme
参考文献
Ciuffreda, Pierangela; Casati, Silvana; Meroni, Giuseppe; Santaniello, Enzo
Tetrahedron, 2013 , vol. 69, # 29 p. 5893 - 5897
反应条件
triethylamine in dichloromethane
T=20°C; 3 h;
参考文献
Zhou, Wenhui; Shultz, John W.; Murphy, Nancy; Hawkins, Erika M.; Bernad, Laurent; Good, Troy; Moothart, Leonard; Frackman, Susan; Klaubert, Dieter H.; Bulleit, Robert F.; Wood, Keith V.
Chemical Communications, 2006 , # 44 p. 4620 - 4622
反应条件
triethylamine in ethanol
6.5 h; Inert atmosphereReflux;
参考文献
Hirano, Takashi; Hasumi, Yosuke; Ohtsuka, Kazuhiro; Maki, Shojiro; Niwa, Haruki; et al.
Journal of the American Chemical Society, 2009 , vol. 131, p. 2385 - 2396
反应条件
sodium hydroxide in methanol; water
5 h; Ambient temperature;
参考文献
Suzuki,N. et al.
Tetrahedron, 1972 , vol. 28, p. 4065 - 4074
参考文献
Hopkins; Seliger; White; Cass
Journal of the American Chemical Society, 1967 , vol. 89, # 26 p. 7148 - 7150
