1: With piperidine; pyridine Knoevenagel-Doebner reaction; Reflux; 2: With hydrogenchloride in water Cooling with ice; optical yield given as percent de;
参考文献
Journal of Organic Chemistry, , vol. 74, # 23 p. 9152 - 9157
Biju, Akkattu T.; Glorius, Frank
Angewandte Chemie - International Edition, 2010 , vol. 49, # 50 p. 9761 - 9764
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反应条件
1: With silver trifluoromethanesulfonate; (S)-(-)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl in toluene T=-50°C; 40 h; Inert atmosphere; 2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone in benzene T=20°C; optical yield given as percent eestereospecific reaction;
