乙基 3-(2-甲氧基苯基)-1H-吡唑-5-羧酸合成路线 （共 2 条）
反应条件
hydrazine in ethanol
T=20°C; 15 h;
参考文献
Cao, Sheldon X.; Feng, Jun; Imaeda, Yasuhiro; Gwaltney, Stephen L.; Hosfield, David J.; Takakura, Nobuyuki; Tang, Mingnam
Patent: US2007/197532 A1, 2007 ;
Location in patent: Page/Page column 48 ;
反应条件
1: C12H16N2O3 With n-butyllithium in tetrahydrofuran; hexane
T=-78 - 20°C; 1 h;
2: oxalic acid diethyl ester in tetrahydrofuran; hexane
T=-78 - 20°C; 16 h;
3: With toluene-4-sulfonic acid in toluene
10 h; Heating; Further stages.;
参考文献
Dang, Tuan Thanh; Dang, Tung Thanh; Langer, Peter
Tetrahedron Letters, 2007 , vol. 48, # 20 p. 3591 - 3593
