1-吡啶-4-哌啶-4-甲酸合成路线 （共 7 条）
反应条件
triethylamine in ethanol; water T=150°C; 96 h;
参考文献
EP1489078 A1, ;
Page 186 ;
EP 1489078 A1
反应条件
triethylamine in ethanol; water T=150°C; 96 h;
参考文献
Guendouz, Farida; Jacquier, Robert; Verducci, Jean
Tetrahedron, 1988 , vol. 44, # 23 p. 7095 - 7108
反应条件
1: triethylamine / ethanol; water / 120 h / 140 °C / |Sealed tube 2: sodium hydroxide / ethanol / |Reflux View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 21 p. 8696 - 8711
反应条件
sodium hydroxide in ethanol Reflux;
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 21 p. 8696 - 8711
反应条件
borane in tetrahydrofuran T=20°C; 12 h;
参考文献
Ajinomoto Co., Inc.
Patent: EP2311810 A1, 2011 ;
反应条件
in tetrahydrofuran; hydrogenchloride
参考文献
Japan Tobacco Inc.
Patent: US6562828 B1, 2003 ;
US 6562828 B1
反应条件
thionyl chloride T=50°C;
参考文献
Ajinomoto Co., Inc.
Patent: EP2311810 A1, 2011 ;
Location in patent: Page/Page column 21 ;
