1: 1.) n-BuLi / 1.) THF, ether, 2a.) 0 deg C, 2 h, 2b.) RT, 2 h 2: 76 percent / 5N HCl / pentane / 2 h View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 42 percent / 5N NaOH / tetrahydrofuran / 20 h / Heating<br />2: 72 percent / diethyl ether / 1.) 0 deg C, 1 h, 2.) RT, overnight<br /> <br /> &nbsp;

&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1696894', constants.ctx, '0')">diethyl ether</a> <br />&nbsp;1.) 0 deg C, 1 h, 2.) RT, overnight;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 75 percent / NaH / petroleum ether / Heating<br />2: 85 percent / H+<br />3: 42 percent / 5N NaOH / tetrahydrofuran / 20 h / Heating<br />4: 72 percent / diethyl ether / 1.) 0 deg C, 1 h, 2.) RT, overnight<br /> <br /> &nbsp;