3-(4-氟苯基)-1-异丙基-1H-吲哚合成路线 （共 17 条）
反应条件
zinc(II) chloride in ethanol T=100 - 105°C; 5 h;
参考文献
Walkup, R. E.; Linder, J.
Tetrahedron Letters, 1985 , vol. 26, # 18 p. 2155 - 2158
反应条件
sodium hydride in N,N-dimethyl-formamide T=20°C; 3 h;
参考文献
Kim, Aejin; Kim, In Su
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 10 p. 3748 - 3751
反应条件
2,6-di-tert-butyl-pyridine; copper(II) bis(trifluoromethanesulfonate) in dichloromethane T=35°C; 48 h;
参考文献
Kim, Aejin; Kim, In Su
Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 10 p. 3748 - 3751
反应条件
1: 80.2 percent / dimethylformamide / 10 h / 100 °C 2: 81 percent / ZnCl2 / ethanol / 5 h / 100 - 105 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 18 p. 2155 - 2158
反应条件
1: 80.2 percent / dimethylformamide / 10 h / 100 °C 2: 81 percent / ZnCl2 / ethanol / 5 h / 100 - 105 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 26, # 18 p. 2155 - 2158
反应条件
1: 2,6-di-tert-butyl-pyridine; copper(II) bis(trifluoromethanesulfonate) / dichloromethane / 48 h / 35 °C 2: sodium hydride / N,N-dimethyl-formamide / 3 h / 20 °C View Scheme
参考文献
Bulletin of the Korean Chemical Society, , vol. 32, # 10 p. 3748 - 3751
反应条件
1: 2,6-di-tert-butyl-pyridine; copper(II) bis(trifluoromethanesulfonate) / dichloromethane / 48 h / 35 °C 2: sodium hydride / N,N-dimethyl-formamide / 3 h / 20 °C View Scheme
参考文献
Bulletin of the Korean Chemical Society, , vol. 32, # 10 p. 3748 - 3751
反应条件
1: With trichlorophosphate in acetonitrile T=5 - 60°C; 4.5 - 7 h; 2: With water T=60°C; 1 h;
参考文献
Clariant Life Science Molecules (Italia) SpA
Patent: EP1477474 A1, 2004 ;
Location in patent: Page column 5 - 6 ;
反应条件
bis(trichloromethyl) carbonate; trichlorophosphate in chlorobenzene T=5 - 80°C;
参考文献
Clariant Life Science Molecules (Italia) SpA
Patent: EP1477474 A1, 2004 ;
Location in patent: Page column 6 ;
反应条件
1: 3-(N-methyl-N-phenylamino)-2-propenal With trichlorophosphate in acetonitrile T=-5 - 7°C; 0.916667 h; Inert atmosphere; 2: 3-(4'-fluorophenyl)-1-(1'-methylethyl)-1H-indole in acetonitrile 3 h; RefluxInert atmosphere;
参考文献
Zacharia, James T.; Tanaka, Takanori; Hayashi, Masahiko
Journal of Organic Chemistry, 2010 , vol. 75, # 22 p. 7514 - 7518
