3-碘氮杂丁烷-1-羧酸苄酯合成路线 （共 4 条）
反应条件
1H-imidazole; iodine; triphenylphosphine in dichloromethane
T=0 - 20°C; Inert atmosphereSchlenk technique;
参考文献
Yi, Jun; Lu, Xi; Sun, Yan-Yan; Xiao, Bin; Liu, Lei
Angewandte Chemie - International Edition, 2013 , vol. 52, # 47 p. 12409 - 12413
Angew. Chem., 2013 , vol. 125, # 47 p. 12635 - 12639,5
反应条件
sodium iodide in acetone
T=20°C; 2 h;
参考文献
Davis, Tyler A.; Danneman, Michael W.; Johnston, Jeffrey N.
Chemical Communications, 2012 , vol. 48, # 45 p. 5578 - 5580
反应条件
sodium iodide in N,N-dimethyl-formamide
T=100°C; Inert atmosphereGlovebox;
参考文献
Cheung, Chi Wai; Ren, Peng; Hu, Xile
Organic Letters, 2014 , vol. 16, # 9 p. 2566 - 2569
反应条件
1: sodium hydrogencarbonate / water / 0 - 20 °C
2: pyridine / dichloromethane / -20 - 20 °C
3: sodium iodide / acetone / 2 h / 20 °C
View Scheme
参考文献
Davis, Tyler A.; Danneman, Michael W.; Johnston, Jeffrey N.
Chemical Communications, 2012 , vol. 48, # 45 p. 5578 - 5580
