6,8-二氟-1,2-二氢萘合成路线 （共 2 条）
反应条件
toluene-4-sulfonic acid in benzene
T=80°C;
参考文献
Martinez
Tetrahedron Asymmetry, 1995 , vol. 6, # 7 p. 1491 - 1494
反应条件
1: (Ph)2PCl2, Et3N / dimethylformamide / 6 h / 85 °C
2: H2 / 10percent Pd/C / ethyl acetate / 3102.9 Torr
3: 6N aq. H2CrO4 / acetone / 20 °C
4: oxalyl chloride, DMF / CH2Cl2 / 20 °C
5: AlCl3 / CS2 / 40 °C
6: NaBH4 / methanol / 0 °C
7: p-TsOH / benzene / 80 °C
View Scheme
参考文献
Martinez
Tetrahedron Asymmetry, 1995 , vol. 6, # 7 p. 1491 - 1494
