2-氨基-6-乙氧基苯并噻唑合成路线 （共 21 条）
参考文献
Chemische Berichte, , vol. 69, p. 88,92
反应条件
sodium nitrite in hydrogenchloride; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; water; acetic acid
参考文献
Dr. Karl Thomae GmbH
Patent: US5919807 A1, 1999 ;
反应条件
hydrogenchloride; copper; sodium nitrite in water T=-5 - 55°C;
参考文献
Cressier, Damien; Prouillac, Caroline; Hernandez, Pierre; Amourette, Christine; Diserbo, Michel; Lion, Claude; Rima, Ghassoub
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 14 p. 5275 - 5284
反应条件
1: With potassium hydroxide; water Reflux; 2: With air
参考文献
Kalwania; Chomal; Choudhary, Savita
Asian Journal of Chemistry, 2011 , vol. 23, # 11 p. 5133 - 5136
参考文献
Pant, Umesh C.; Gaur, B. S.; Chugh, Manju
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 189 - 190
参考文献
Rice,L.M. et al.
Journal of Medicinal Chemistry, 1968 , vol. 11, # 1 p. 183 - 185
反应条件
1: With water; hydrogen bromide in acetic acid T=150°C; 0.0555556 h; Microwave; 2: With sodium hydrogencarbonate in water pH=8;
参考文献
US2007/93488 A1, ;
Page/Page column 7 ;
反应条件
1: With sulfuric acid in water; ethylene glycol
T=80°C; 0.5 h;
2: With hydrazine
T=140°C; 5 h;
参考文献
Liu, Da-Chuan; Deng, Xian-Qing; Wang, Shi-Ben; Quan, Zhe-Shan
Archiv der Pharmazie, 2014 , vol. 347, # 4 p. 268 - 275
反应条件
1: With potassium hydroxide in water
17 h; Reflux;
2: With methyl iodide in water
T=20°C; 1 h;
参考文献
Hari, Durga Prasad; Hering, Thea; Koenig, Burkhard
Organic Letters, 2012 , vol. 14, # 20 p. 5334 - 5337,4
参考文献
Horgan,S.W. et al.
Journal of Medicinal Chemistry, 1975 , vol. 18, p. 315 - 318
