1,4-环己二甲酸二甲酯合成路线 （共 39 条）
反应条件
hydrogenchloride; thionyl chloride in methanol 1 h; Cooling with iceReflux;
参考文献
ACHAOGEN, INC.; KASAR, Ramesh; LINSELL, Martin Sheringham; AGGEN, James Bradley; LU, Qing (Jane); WANG, Dan; CHURCH, Tim; MOSER, Heinz E.; PATTEN, Phillip A.
Patent: WO2012/154204 A1, 2012 ;
Location in patent: Page/Page column 83; 84 ;
反应条件
hydrogen; Ru5PtSn; silica gel in ethanol T=99.85°C; P=15001.2 Torr; 24 h;
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 29 p. 4782 - 4785
反应条件
hydrogen; palladium on activated charcoal in dichloromethane T=20°C;
参考文献
WO2012/82725 A1, ;
Page/Page column 38 ;
反应条件
hydrogen; Ru5PtSn; silica gel in ethanol T=119.85°C; P=30002.4 Torr; 8 h; Further byproducts given;
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 29 p. 4782 - 4785
反应条件
hydrogen; W 2 Raney nickel in tetrahydrofuran; methanol T=100 - 105°C; P=82743.7 Torr; 15 h;
参考文献
Della, Ernest W.; Tsanaktsidis, John
Australian Journal of Chemistry, 1985 , vol. 38, # 11 p. 1705 - 1718
反应条件
hydrogen; Ru6Sn; silica gel in ethanol T=99.85°C; P=15001.2 Torr; 8 h; Product distribution; Further Variations:Catalystsreaction times;
参考文献
Angewandte Chemie - International Edition, , vol. 40, # 24 p. 4638 - 4642
反应条件
hydrogen; Ru5PtSn; silica gel in ethanol T=99.85°C; P=15001.2 Torr; 24 h; Product distribution; Further Variations:CatalystsTemperaturesPressures;
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 29 p. 4782 - 4785
反应条件
5 palladium on Al2O3 T=300 - 325°C; 7.5 h; Inert atmosphere;
参考文献
WO2012/82725 A1, ;
Page/Page column 37 ;
反应条件
hydrogen; Pt1Ru5; silica gel in ethanol T=99.85°C; P=15001.2 Torr; 8 h; Product distribution; Further Variations:Catalystsreaction times;
参考文献
Angewandte Chemie - International Edition, , vol. 40, # 24 p. 4638 - 4642
反应条件
1.1: iodine / diethylene glycol dimethyl ether / 48 h / 200 °C / 13963.4 Torr 1.2: 14 h / Reflux 2.1: hydrogen / palladium on activated charcoal / dichloromethane / 20 °C View Scheme
