1-氯-3-苯氧基-2-丙酮合成路线 (共 8 条)
反应条件
1: 1-chloro-3-phenoxy-2-propanone With alcohol dehydrogenase from Lactobacillus brevis; NADPH; isopropyl alcohol T=30°C; pH=7.5; 6 h; aq. bufferEnzymatic reaction; 2: sodium cyanide With halohydrin dehalogenase from Mycobacterium sp. GP1 T=30°C; pH=7.5; 18 h; aq. bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 14 p. 2293 - 2298
反应条件
1: 1-chloro-3-phenoxy-2-propanone With alcohol dehydrogenase from Lactobacillus brevis; NADPH; isopropyl alcohol T=30°C; pH=7.5; 6 h; aq. bufferEnzymatic reaction; 2: sodium cyanide With halohydrin dehalogenase from Mycobacterium sp. GP1 T=30°C; pH=7.5; 18 h; aq. bufferEnzymatic reaction; optical yield given as percent ee;
参考文献
European Journal of Organic Chemistry, , # 14 p. 2293 - 2298
反应条件
in diethyl ether T=25°C; 3 h;
参考文献
Kim, Yong Hae; Jung, Sun Ho
Tetrahedron Letters, 1981 , vol. 22, # 25 p. 2371 - 2372
反应条件
isopropyl alcohol in various solvent(s) T=30°C; pH=7.5; 5 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 8-9 p. 1399 - 1404
反应条件
Agrobacterium radiobacter AD1 halohydrin dehalogenase HheC; isopropyl alcohol T=30°C; 24 h; aq. bufferEnzymatic reaction; optical yield given as percent eestereoselective reaction;
参考文献
Schrittwieser, Joerg H.; Lavandera, Ivan; Seisser, Birgit; Mautner, Barbara; Lutje Spelberg, Jeffrey H.; Kroutil, Wolfgang
Tetrahedron Asymmetry, 2009 , vol. 20, # 4 p. 483 - 488
反应条件
1: NaBH4
View Scheme
参考文献
Longoni,R. et al.
Helvetica Chimica Acta, 1977 , vol. 60, p. 103 - 111
反应条件
1: NaBH4
3: HCO2H
View Scheme
参考文献
Longoni,R. et al.
Helvetica Chimica Acta, 1977 , vol. 60, p. 103 - 111
反应条件
1: NaBH4
3: Py
View Scheme
参考文献
Longoni,R. et al.
Helvetica Chimica Acta, 1977 , vol. 60, p. 103 - 111