3-[2-(三氟甲基)苯基]丙酸合成路线 （共 3 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate Catalytic hydrogenation;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 14 p. 1519 - 1522
反应条件
1: With potassium carbonate; Pd-Tedicyp catalyst in N,N-dimethyl-formamide T=110°C; Heck reaction; 20 h; 2: With sodium hydroxide; water in N,N-dimethyl-formamide T=50 - 80°C;
参考文献
Lemhadri, Mhamed; Doucet, Henri; Santelli, Maurice
Tetrahedron, 2004 , vol. 60, # 50 p. 11533 - 11540
反应条件
sodium carbonate; magnesium sulfate in thionyl chloride; n-heptane; dichloromethane; ethyl acetate
参考文献
Strobel, Hartmut; Wohlfart, Paulus; Safarova, Alena; Walser, Armin; Suzuki, Teri; Schonafinger, Karl; Dharanipragada, Ramalinga M.
Patent: US2003/55093 A1, 2003 ;
